PIRFENIDONE INHIBITS HYPOXIC PULMONARY HYPERTENSION THROUGH THE NADPH/ROS/P38 PATHWAY IN ADVENTITIAL FIBROBLASTS IN THE PULMONARY ARTERY

Pirfenidone Inhibits Hypoxic Pulmonary Hypertension through the NADPH/ROS/p38 Pathway in Adventitial Fibroblasts in the Pulmonary Artery

Hypoxic pulmonary hypertension (HPH) is a devastating disease characterized by progressive vasoconstriction and vascular remodeling.Pirfenidone (PFD) inhibits the progression of HPH, though the molecular mechanisms remain unknown.This study is aimed at determining the role and mechanism of PFD in HPH in human pulmonary artery adventitial fibroblast

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Matura final examination in psychology: some metric properties

Matura in Slovenia consist of five subjects.The three compulsory subjects are: Mother Tongue, Mathematics and Foreign Language.Psychology is one of the two optional subjects (electives) that must be chosen from a wide range of natural sciences, foreign and classical languages, humanities, social sciences, and technical or vocational subjects.The ex

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The Isle of The Dead Benchmark, the Sydney, Fort Denison Tide Gauge and the Ipcc Ar5 Chapter 13 Sea Levels Revisited

The paper revisits the Isle of the Dead benchmark and the Sydney, Fort Denison tide gauge to confirm that long term, high quality tide gauges are acceleration free, consistently to the analysis of key sites suggesting the sea levels are not sharply raising following the carbon dioxide emissions.The paper Mandolines also discusses the flaws of the I

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